An article of clothing can be used to reduce or prevent the occurrence of prolonged skin-on-skin contact, rashes, irritation, intertrigo, infections, discomfort, or chaffing. Such an article of clothing has a moisture management material made up of at least an outer layer, an inner layer, and a tab. The moisture management material is attached to a portion of the article of clothing via a tab of the moisture management material. The moisture management material may be of various shapes and sizes and preferably fits within a prescribed area of the article of clothing. The moisture management material may be variably positioned within the article of clothing to provide differing results such as additional support and/or moisture absorbing or moisture moving where necessary. Preferably the article of clothing is a brassiere but may be a shirt, diaper, pants, socks, panties, or other undergarments.