HINMAN, ANDREW W.,JANKOWSKI, ORION D.,WESSON, KIERON E.
申请号:
CA2729227
公开号:
CA2729227C
申请日:
2009.06.23
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Disclosed herein are methods of treating or suppressing oxidative stressdisorders includingmitochondrial diseases, impaired energy processing disorders,neurodegenerative diseasesand diseases of aging are disclosed, as well as compounds useful in themethods of theinvention, such as 2-heterocyclylaminoalkyl-(p-quinone) derivatives of FormulaI(see formula I)where R is selected from the group consisting of:(see formula II) and (see formula III)where * indicates the point of attachment of R to the remainder of themolecule; n is 0 or 1;and R1-R4, Het, M and M' are as defined herein.