AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION;THE UNIVERSITY OF SYDNEY
发明人:
MIDDLETON, RYAN,BANATI, RICHARD,LIU, GUO JUN
申请号:
CA2905565
公开号:
CA2905565A1
申请日:
2014.03.13
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention relates to transgenic animal models. Specifically, the present invention relates to transgenic animal models for applications associated with TSPO-related normal physiology, diseases and disorders. The present invention features a transgenic nonhuman animal comprising cells with at least one copy of a non-functional, endogenous TSPO gene. Also disclosed are compounds for investigating or modulating TSPO-related functions.