An aerosol-generating system is provided, including an aerosol-generating device including a heater element； an aerosol-generating article, including a medicament source and a volatile delivery enhancing compound source； and at least one resilient member provided in the aerosol-generating device or the aerosol-generating article and being resiliently biased against the heater element, wherein at least one of the medicament source and the volatile delivery enhancing compound source contacts the at least one resilient member, and the aerosol-generating system is configured to heat the medicament source and the volatile delivery enhancing compound source of the aerosol-generating article so that the medicament source has a higher temperature than that of the volatile delivery enhancing compound source.
