#$%^&*AU2018100981A420180816.pdf#####ABSTRACT OF THE DISCLOSURE The present invention relates to the field of medical chemistry and particularly relates to a sweet potato sitosterol glucoside saturated fatty acid ester and extract as well as preparation methods and application thereof. The sweet potato sitosterol glucoside 5 saturated fatty acid ester extract has a certain inhibition effect on MCF-7, and the inhibition effect is very weak under low concentration； the sweet potato sitosterol glucoside saturated fatty acid ester has a good inhibition effect on MCF-7, wherein sweet potato sitosterol glucoside palmitate has the highest inhibition effect on MCF-7 breast cancer cells, and the anti-tumor activity is reduced to a certain degree due to 10 increase and decrease of carbon chains； and the inhibition effect of the sweet potato sitosterol glucoside palmitate on tumors is obviously higher than that of sweet potato sitosterol glucoside linoleate and sweet potato sitosterol glucoside. -28-
