A pharmaceutical composition for treatment of inflammation or pain or chronic inflammation is liquid at normal human body temperature, namely 37°C, solid at room temperature, namely 20°C, and comprises: a) 25% to 31 % by weight of a non-steroidal anti-inflammatory drug (NSAID) b) 34% to 40% by weight of a lipid which is solid at room temperature, namely 20°C c) 22% to 28% by weight of a lipid which is a liquid at room temperature, namely 20°C and d) 7% to 13% by weight of a stabilizing agent comprising liquid glycol polymer.