A medical syringe is provided, which is excellent in the sealability and the slidability of a gasket thereof. The syringe includes a hollow cylindrical syringe barrel (11), and a gasket (13) fitted in the syringe barrel (11) . The gasket (13) includes a main body of an elastic material laminated with an inert resin film, and has a circumferential surface portion (17) substantially kept in contact with an inner surface (16) of the syringe barrel (11), and an annular projection (22) provided on the circumferential surface portion (17) as extending circumferentially of the circumferential surface portion (17). The projection (22) has a contact surface portion kept in contact with the inner surface (16) of the syringe barrel (11) and having a width of not less than 30 µm and not greater than 40 µm. The circumferential surface portion (17) has non-contact surface portions located out of contact with the inner surface (16) of the syringe barrel (11) on widthwise opposite sides of the projection (22) and having a width of not less than 30 µm.