Device for sampling tear fluid that comprises:- an extraction element (202) adapted to be applied on the eye to draw tear fluid therefrom, comprising at least one tube (209) and a distal portion (201) with at least one opening (207),- a collection vessel (203), connected to said tube (209),- suction means (210) adapted to continuously draw tear fluid from the eye to the collection vessel (203), through the extraction element (202) for a period higher than 10 minutes once the extraction element (202) is in place.