This report is also provided with these antibody and using the method for these antibody, to reduce low density lipoprotein cholesterol (LDL-C). (a) antibody :(a) do not cause to block by more chlorodiphenyls and to low-density (LLR) receiver (LLLR) receiver (b) degradation (L) (d) of low-density receiver is inhibited to be measured by Polychlorinated biphenyls. 5th require: the antibody of antibody: antibody includes: the chain area of heavy type (a), including heavy human severe head part, heavy-duty chain 3(CDR3) a third complementary region and heavy-duty chain 4(FR4) area. A, (b) a variable slight chain area, including slight mankinds chain part, slight chain 3(CDR3) and a slight chain on the 4th component part, (i) heavy-duty chain 3(CDR3) determining area include amino acid (A/N) MD sequences (A/F/S/V/Y) (SSEQ ID NSD 14) (2) the third complementarity on slight chain determines that the Variable Area in area includes the sequence of amino acid sequence. LQWSSDPPT(SEQ ID NS 26).