The present invention concerns an oil-in-water emulsion wherein the oil droplets ofa diameter in the range of 5 nm to hundreds of micrometers exhibit a nano-sized self-assembled structurization with hydrophilic domains having a diameter sizein the range of 0.5 to 200 nm, due to the presence of a lipophilic additive and theoil-in-water emulsion contains an active element being present in the range comprisedbetween 0.00001 and 79 % based on the total composition.