The present disclosure relates generally to the field of medical devices for accessing body lumens. In particular, the present disclosure relates to medical devices, systems and methods for targeted access to and cutting of a body lumen opening with an electrode. In embodiments, a device may comprise a flexible elongate tube, an articulation wire may extend at least partially along the tube within a lumen from the proximal end of the tube and have a distal end connected to a distal portion of the elongate tube, a portion of the articulation wire may extend external to the elongate tube, an electrode may be disposed on the distal portion of the tube distal to the distal end of the articulation wire, and a conductive wire may extend along and within the tube in electrical communication with the electrode.