(R) -3- (4- (7H-PYRROLO [2,3-D] PYRIMIDIN-4-IL) -1H-PIRAZOL-1-IL) -3 CYCLEPENTILPROPANONITRILA JANUS KINASE INHIBITOR METABOLIES

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专利权人:

INCYTE CORPORATION

发明人:

JAMES D. RODGERS,ARGYRIOS G. ARVANITIS,JACK GUOEN SHI

申请号：

BRPI0812563

公开号：

BRPI0812563A2

申请日:

2008.06.12

申请国别(地区):

BR

年份:

2015

代理人:

摘要：

The present invention provides active metabolites of 3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.

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