Philippe Denoel;Pierre Duvivier;Jan Poolman;Ralph Leon Biemans;Dominique Boutriau;Carine Capiau
发明人:
Ralph Leon Biemans,Dominique Boutriau,Carine Capiau,Philippe Denoel,Pierre Duvivier,Jan Poolman
申请号：
US11917709
公开号：
US09931397B2
申请日:
2006.06.23
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present application relates to an immunogenic composition comprising at least 2 conjugates of N. meningitidis capsular saccharide and protein carrier, wherein said conjugates comprise at least 2 different N. meningitidis capsular saccharides selected from the group consisting of MenA, MenC, MenY and MenW, wherein at least one capsular saccharide is conjugated to a protein carrier with a saccharide:protein ratio (w/w) between 1:2-1:5, and wherein at least one different capsular saccharide is conjugated to a protein carrier with a saccharide:protein ratio (w/w) between 5:1-1:1.99.
