[Problem to be Solved by the Invention]A main object of the present invention is to provide a novel pyridine derivative or a pharmaceutically acceptable salt thereof.[Means of Solving the Problems]A pyridine derivative or a pharmaceutically acceptable salt represented by the following genaral formula [1] or a pharmaceutically acceptable salt thereof.In formula [1], R represents an aryl group or a heteroaryl group, wherein each of the aryl group and the heteroaryl group may be substituted by one or two substituents independently selected from the group consisting of an optionally substituted alkyl group, a hydroxy group, a halogen atom and a group represented by general formula [2]. In formula [2], -L1-L2-L3-RAL1 and L3 independently represent a single bond, an alkylene group or a cycloalkylene group L2 represents a single bond, O, or NRB RB represents H or an optionally substituted alkyl group RA represents H, an amino group, a cyano group, a hydroxy group, an alkoxy group, an aryl group, a monoalkylamino group, a dialkylamino group, a carbamoyl group, an alkyloxycarbonyl group, a monoalkylaminocarbonyl group, a dialkylaminocarbonyl group, an alkylcarbonylamino group, a saturated heterocyclic group, an optionally substituted alkyl group, an optionally substituted cycloalkyl group or an optionally substituted heteroaryl group.