A one-piece hand-held dermatoscope have two magnifier lenses, a larger rectangular-shaped lens between two and three times magnification power, and a smaller circular lens between eight and 15 times magnification power. A polarizer is position between the lens and a patients skin. In one embodiment, the polarizer is radial, such that cross-polarization is achieved when the light reflect off the skin and passes through it a second time. In another embodiment, the portion of the polarizer through which the light passes to the skin is linear in a first direction, and the portion through which the light passes back from the skin is linear in a second direction that is perpendicular to the first direction, enabling cross-polarization.