DERIVE DE N-HYDROXYFORMAMIDE ET PRODUIT PHARMACEUTIQUE LE CONTENANT

• 收藏
• 分享

专利权人:

LTD.;KAKEN PHARMACEUTICAL CO.

发明人:

KAWAI, KENTARO,MIYAMOTO, SHIGERU,SHIMANO, MASANAO,HAINO, MAKOTO

申请号：

CA2804918

公开号：

CA2804918C

申请日:

2011.07.05

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

Described embodiments relate to a compound representedby the following general formula (I) which has ADAM17 inhibitoryactivity, or a salt thereof, or a solvate thereof:(see formula I)wherein X represents a phenylene group； Y represents a hydrogenatom, -(CH2)m R1 or the like； R1 represents -NR5COR2, -NR5SO2R2 or-NR3R4； R2 represents a C1-C6 alkyl group, an aryl group, or aC1-C6 alkoxy group； R3 and R4 represent a C1-C6 alkyl group andthe like； R5 represents a hydrogen atom or a C1-C6 alkyl groupor the like； m indicates an integer of from 0 to 4； and Zrepresents a hydrogen atom or a C1-C6 alkyl group.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/