The present invention relates to a respiratory tubing set for controlling breathing of a patient. A tubing set for controlling breathing of a patient includes a respiratory conduit. The respiratory conduit is configured to be coupled to a patient interface device and is further configured to be coupled to a pressurized air generating device. The respiratory conduit includes at least two airflow control devices, positioned between the patient interface device and the pressurized air generating device that cooperate to closely control the CO2 levels in the patient's bloodstream through the control of the patient's respiration.