CELEWICZ, LECH,KACPRZAK, KAROL,BARANIAK, DAGMARA,LEWANDOWSKA, MARTA,RUSZKOWSKI, PIOTR
申请号:
PL14716996
公开号:
PL3105243T3
申请日:
2014.03.04
申请国别(地区):
PL
年份:
2018
代理人:
摘要:
2′,3′-dideoxy-5-fluorouridine derivatives have general formula 1: wherein: R1 denotes cinchona alkaloid fragment with defined absolute configuration at C-8 and C-9 atoms. A process for the manufacture of 2′,3′-dideoxy-5-fluorouridine derivatives of general formula 1 and application of 2′,3′-dideoxy-5-fluorouridine derivatives of general formula 1 in the anticancer treatment of breast cancer, cervical cancer and hepatic cancer are also indicated.