Barry S. Coller,Craig Thomas,Marta Filizola,Joshua McCoy,Wenwei Huang,Min Shen
申请号:
US13810587
公开号:
US09066948B2
申请日:
2011.07.15
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to compounds of formula P-1 and related compounds and compositions useful for inhibiting and/or reducing platelet deposition, adhesion and/or aggregation. The definitions of A, Y, R1, R2, Ra, Ra′, Rb, Rb′, Rc, Rc′, Rd, Rd′, Re, and Re′ are provided herein. The present invention further relates to methods for the treatment or prophylaxis of thrombotic disorders, including stroke, myocardial infarction, unstable angina, peripheral vascular disease, abrupt closure following angioplasty or stent placement and thrombosis as a result of vascular surgery.