Zhiqiang Zhao;Hubert Josien;Wen-Lian Wu;Martin Domalski;Dmitri A. Pissarnitski;Thavalakulamgar Sasikumar;David Cole;Duane A. Burnett
发明人:
Duane A. Burnett,Zhiqiang Zhao,David Cole,Hubert Josien,Dmitri A. Pissarnitski,Thavalakulamgar Sasikumar,Wen-Lian Wu,Martin Domalski
申请号：
US13990948
公开号：
US20130261140A1
申请日:
2011.12.01
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention is directed to novel tricyclic heterocycles of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved. I
