БЕРК Роберт М. (US),ИМ Вха Бин (US),ВИТКАП Скотт М. (US)
申请号：
RU2013129262/15
公开号：
RU2013129262A
申请日:
2011.11.30
申请国别(地区):
RU
年份:
2015
代理人:
摘要：
1. A method for treating a skin defect comprising administering a composition containing a therapeutically effective amount of a compound having the structure: wherein each dashed line represents the presence or absence of a double bond； R, R, R and R are each independently selected from H and C-C linear alkyl； R is halogen C 1-6 alkyl or C 1-6 alkenyl； R is H, C 1-6 alkyl, C 1-6 alkenyl, their salt or their amine； n is 0-7； and X is S or O, characterized in that said administration treats said skin defect. 2. The method according to claim 1, characterized in that R is H, R is H, and X is S.3. The method according to claim 1, characterized in that R and R are CH.4. The method according to claim 1, characterized in that R is Cl.5. The method according to claim 1, characterized in that the compound is: .6. The method according to claim 1, characterized in that the skin defect is a superficial wound, scar or wrinkle. The method according to claim 1, characterized in that the composition is administered subcutaneously, subdermally or transdermally, intradermally or locally. The method according to claim 6, characterized in that the introduction reduces the formation of a type of scar selected from the group consisting of a hypertrophic scar, an inverted scar, stretch marks, and a combination thereof. The method according to claim 6, characterized in that the skin defect is a wrinkle. The method according to claim 1, characterized in that the composition is administered in an area selected from the group consisting of a face, neck, arms, trunk, back, legs, and combinations thereof. The method according to claim 1, characterized in that the composition is administered at a time selected from the group consisting of the time before the surgical incision, during the surgical operation, after the operation, as well as their combination. The method according to claim 1, characterized in that the introduction minimizes the formation of1. Способ лечения дефекта кожи, включающий
