GlaxoSmithKline Intellectual Property Development Limited
发明人:
Kumpalume, Peter,Schon, Oliver,Donahue, Christine Patricia,Evindar, Ghotas,Israel, David I.,Paolella, David,Kuai, Letian,Prabhu, Ninad V.
申请号：
AU2014330781
公开号：
AU2014330781A1
申请日:
2014.10.01
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
Compounds useful for affinity chromatography as presented, more particularly for use in affinity chromatography to purify serum albumin, especially human serum albumin (HSA) and fusion proteins thereof. Methods for extending the half-life of therapeutic agents are also presented, particularly therapeutic peptide agents and small molecules, such as by conjugation of compounds described herein to the therapeutic peptide or small molecule, which, upon administration, binds to HSA, thereby providing a prolonged release of the therapeutic agent.
