AKT ISOZYME-SPECIFIC COVALENT INHIBITORS DERIVED FROM REDOX-SIGNALING LIPIDS

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专利权人:

Cornell University

发明人:

Yimon AYE,Xuyu LIU,Marcus J.C. LONG

申请号：

US16619245

公开号：

US20200148682A1

申请日:

2018.06.06

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present invention is directed to a compound of Formula (I) wherein A, X, Y, R1, R2, R3, R4, and n are as described herein. The present invention also relates to: 1) a method of treating cancer using a compound of Formula (I) and 2) a method of inhibiting pan-Akt in a cell or a tissue using a compound of Formula (I).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/