DERIVES DE IMIDAZO[1,2-A]-PYRAZOLO[4,3-E]-PYRIMIDIN-4-ONE AVEC ACTIVITE INHIBITRICE DE LA PDE1

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专利权人:

Inc.;Intra-Cellular Therapies

发明人:

申请号：

EP15829416.5

公开号：

EP3177627B1

申请日:

2015.08.07

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

The invention relates to novel inhibitors of phosphodiesterase 1 (PDE1), useful for the treatment of diseases or disorders characterized by disruption of or damage to certain cGMP/PKG mediated pathways (e.g., in cardiac tissue). The invention further relates to pharmaceutical composition comprising the same and methods of treatment of cardiovascular disease and related disorders, e.g., congestive heart disease, atherosclerosis, myocardial infarction, and stroke.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/