NHO, YOUN HWA,노윤화,LEE, JONG SUNG,이종성,MOON, SEONG JOON,문성준,NHO, YOUN HWAKR,LEE, JONG SUNGKR,MOON, SEONG JOONKR
申请号：
KR1020150003483
公开号：
KR1020160086483A
申请日:
2015.01.09
申请国别(地区):
KR
年份:
2016
代理人:
摘要：
The present invention relates to a skin-whitening cosmetic composition containing a Polygoni multiflori Ramulus extract as an active ingredient. According to the present invention, the Polygoni multiflori Ramulus extract inhibits expression of gene encoding tyrosinase, tyrosinase related protein-1 (TRP-1), tyrosinase related protein-2 (TRP-2), or microphthalmia-associated transcription factor (MITF) while promoting activity of LIVER X RECEPTOR (LXR), thereby exhibiting skin-whitening effects by inhibiting melanin biosynthesis.본 발명은 야교등 추출물을 유효성분으로 함유하는 피부 미백용 화장료조성물에 관한 것이다.본 발명에 따르면, 본 발명의 야교등 추출물은 티로시나아제(tyrosinase), TRP-1(tyrosinase related protein-1), TRP-2(tyrosinase related protein-2) 또는 MITF((microphthalmia-associated transcription factor)의 유전자 발현을 억제하고, LXR(Liver X Receptor) 활성을 촉진시킴으로써 멜라닌 생합성을 억제하여, 결론적으로 피부 미백 효과를 나타낼 수 있다.
