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Oil dispersions of nAChR binding neonicotinoids
专利权人:
Victor Casaña Giner
发明人:
Victor Casaña Giner,Miguel Gimeno Sierra,Bárbara Gimeno Sierra
申请号:
US13254785
公开号:
US08293733B2
申请日:
2010.03.04
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Selective insect neonicotinoids is a class of pesticide active ingredients that share some characteristics in their chemical structures and bind to the nAChR acetylcholine receptors. Formulation of such compounds in oil suspension or oil dispersion is challenging due to their electrostatic interactions of the heteroatoms in oily media, that lead to irreversible flocculation or diminished homogeneicity and bleeding of such oil dispersions. Imidacloprid, Thiamethoxam, Thiachloprid, Nitenpyram, Acetamiprid, Clothianidin and Dinetofuran and derivatives thereof with nAChR binding ability are successfully formulated in oil suspension with the use of certain copolymeric anionic fatty-acid based dispersants, sorbitan derivatives, ionic surfactants, other non-ionic surfactants and inorganic polyvalent cationic salt dispersed in the oil. The formulations this way produced show excellent storage stability properties regarding physiochemical parameters, including stability of the neonicotinoid active ingredient, reduced bleeding, and complete redispersibility. Further, they show excellent biological efficacy due to the reduced and homogeneous particle size below 2 μm when diluted—emulsified—in water.
来源网站:
中国工程科技知识中心
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