The present invention provides a device configured to mechanically remove a fat phase from at least one adipose tissue, the device comprising a first pressing element and a second pressing element. Furthermore, there is provided a method for preparing a preparation comprising a fat-depleted adipose tissue, the method comprising: mechanically removing a fat phase from at least one adipose tissue. In addition, there is provided a preparation comprising a fat-depleted adipose tissue, wherein the fat-depleted adipose tissue is prepared by mechanically removing a fat phase from at least one adipose tissue.
