A cartridge of an intraocular lens inserter comprises an insertion nozzle, having a distal insertion channel; an intra-ocular lens (IOL)-folding stage, to receive and to fold an IOL, proximal to the insertion nozzle, and having a proximal insertion channel; and an IOL-guiding structure. The IOL-guiding structure can include a first proximal guiding groove, or a first proximal guiding rib, or both, formed in the IOL-folding stage. An intraocular lens inserter comprises an inserter cylinder; a push-rod, partially in the inserter cylinder; a cartridge-receiving insertion end, to receive a cartridge that includes an insertion nozzle, having a distal insertion channel; an IOL-folding stage, proximal to the insertion nozzle, having a proximal insertion channel; and an IOL-guiding structure.