Wen-Bin Ho,Hongda Zhao,Shaojiang Deng,Danny Ng,Lee R. Wright,Min Wu,Xiaoti Zhou,Michael P. Arend,Lee A. Flippin
申请号：
US14383874
公开号：
US09409892B2
申请日:
2013.03.08
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to novel compounds of formula (I), and compositions capable of inhibiting PHD1 enzyme activity selectively over other isoforms, for example, PHD2 and/or PHD3 enzymes. The invention also relates to compounds of formula (I) for use in disorders such as muscle degeneration, colitis, IBD, and certain ischemias.
