PURPOSE: An anti-wart pharmaceutical composition containing a soluble extract of a Solanum plant is provided to treat wart without side effects. CONSTITUTION: An anti-wart pharmaceutical composition contains a soluble extract of a Solanum plant. The soluble extract contains 60 wt% or more of solamargine and solasonine. The pharmaceutical composition is used for treating common wart, flat wart, plantar wart, or genital wart. The pharmaceutical composition is used by topical administration. The pharmaceutical composition further contains water, alcohol, glycol, hydrocarbon, wax, preservative, antioxidant, surfactant, absorbing agent, stabilizing agent, gelling agent, wetting agent, smell absorbent, perfume, pH adjusting agent, chelating agent, emulsifier, blocking agent, softener, thickening agent, solubilizing agent, coloring agent, dispersing agent, or a combination thereof. [Reference numerals] (AA) Time(weeks)； (BB) 0 week； (CC) Fourth week； (DD) Eighth week솔라눔 속 식물의 수용성 추출물을 포함하는 항사마귀 약학적 조성물로서, 상기 수용성 추출물은 60% 이상의 솔라마진 및 솔라소닌을 포함하는 것인 항사마귀 약학적 조성물이 본 명세서에 개시된다. 또한, 상기 수용성 추출물을 치료가 필요한 개체에 투여하는 것을 포함하는, 사마귀 치료를 위한 방법이 개시된다.
