David L. Robbins;Pratik Multani;Paul Grayson;Daniel Shoemaker;Caroline Desponts;John Mendlein
发明人:
Daniel Shoemaker,Pratik Multani,Caroline Desponts,David L. Robbins,Paul Grayson,John Mendlein
申请号:
US13816723
公开号:
US20140030232A1
申请日:
2011.08.12
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention provides improved methods for cell therapy. In particular, the invention provides therapeutic compositions of modified hematopoietic stem and/or progenitor cells having improved engraftment and homing properties, and methods of making the therapeutic composition. The invention further provides methods of improving the efficacy of hematopoietic stem and progenitor cell transplantation including transplanting the therapeutic composition to subjects in need of hematopoietic system reconstitution.