Hitherto unknown compound that promotes secretion of human-derived antimicrobial peptide, process of preparation and composition with same as active ingredient
PARK, Byoeung-Deog,BAE, Jong-Hwan,JEONG, Se-Kyoo,GWAK, Hyoung-Sub
申请号:
DK10856464
公开号:
DK2617707T3
申请日:
2010.08.27
申请国别(地区):
DK
年份:
2017
代理人:
摘要:
The present invention relates to a novel compound having an acceleration effect on the secretion of human ² -defensin, LL-37, which is a human-derived anti-microbial peptide, a method for preparing same, and a composition for accelerating the secretion of anti-microbial peptide having same as an active ingredient, and the compound and the composition using same of the present invention enhance the anti-microbial effect and the immunity control effect that the anti-microbial peptide has in the body by accelerating the secretion of the anti-microbial peptide in the body. The composition having the compound as an active ingredient of the present invention accelerates the secretion of innate anti-microbial peptide in the tissues and the organs in the body including the skin and can be administered through various courses including external application and oral administration, overcomes the problem of safety, the problem of resistant bacteria development, and the limitations of administration courses in a conventional anti-microbial agent, and demonstrates effective anti-microbial action.