Indiana University Research and Technology Corporation
发明人:
EKSER, Burcin
申请号:
AU2018352842
公开号:
AU2018352842A1
申请日:
2018.10.17
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
Provided herein are synthetic, three-dimensional (3D) bioprinted tissue constructs comprising porcine cells and methods of producing and using the same. The synthetic 3D bioprinted tissue constructs are fabricated by bioprinting spheroids comprising porcine cells, including genetically engineered cells, on a microneedle mold and fusing the spheroids to form an engineered tissue construct. Also provided are methods of using scaffold-free 3D bioprinted tissue constructs for applications related to drug screening and toxicity screening.