Compounds of the formula I ** Formula ** wherein R1 represents A, R2 represents A, (CH2) nAr or (CH2) nHet, R1 and R2, together with the N atom to which they are attached, represent isoindolyl, R3 represents Hal, OH, CN, NO2, C (O) H, NH2, COOH, COOA, C>； = CH, C≡C-CH2OH, CONH2, CONHA, CONAA ', SO2NH2, NHCONH2, XA, X- (CH2) nAr or X- (CH2) nHet, where X represents: a bond -O-, -CO-, -CO2-, -C (O) NH-, -C (O) NA ', -S-, -SO- , SO2-, -SO2NH-, -SO2NA'-, -NH-, -NA'-, -NHSO2-, - NA'SO2-, -NHCO-, -NA'CO-, -NHCONH- or -NA'CONH -, R3 'represents H, A, Hal, OA or CN, A, A', respectively independently of each other, represent unbranched or branched alkyl with 1- C atoms, where one, two or three groups Non-contiguous CH2 or CH can be replaced by O, S, SO, SO2, CO, NH, NR5 15 and / or by groups -CH>； = CH and / or also 1-5 H atoms can be replaced by F, Cl , Br and / or R4, or cycloalkyl with 3-7 atoms of C, A and A ', together with the N atom to which they are attached, also represent a saturated monocyclic heterocycle unsubstituted or mono-, di-, or tri- substituted by Hal, A, (CH2) nOH, (CH2) nOA and / or>； = O (carbonyl oxygen), which may contain in addition to 1 at 3 atoms of N, O and / or S, R4 represents COOR6, CN, CONR6R7, NR6R7, NHCOR6, NHCOOR6, NR6CONR6R7 or OR6, R5 represents cycloalkyl with 3-7 C atoms, cycloalkylalkylene with 4-10 C atoms , Alk or unbranched or branched alkyl with 1-6 C atoms, where one, two or three non-contiguous CH2 or CH groups can be replaced by O, CO, S, SO, SO2, NH and / or 1- 5 H atoms can be replaced by F and / or Cl, R6, R7, respectively independently of each other, represent H or alkyl with 1-5 C atoms, where 1-3 CH2 or CH groups do not contiguous can be replaced by O, CO, S, SO, SO2, NH, NMe or NEt and / or also 1-5 H atoms can be replaced by F and / or Cl, R6 and R7, together they also represent an alkylene chain with 2, 3, 4, 5 or 6 C atoms, where 1-3 non-contiguous C atoms can be replaced by O, CO, S, SO, SO2, NH, NR5, NCOR5 or
