PURPOSE: A composition conaining Oldenlandia diffusa extract for skin cosmetic or beauty as an active ingredient is provided to promote differentiation of human mesenchymal stem cells to adipocytes. CONSTITUTION: A composition for differentiation of adipocyte contains Oldenlandia diffusa extract as an active ingredient. The composition is for increasing adipose tissue. The composition promotes differentiation of human mesenchymal stem cells to adipocyte. The human mesenchymal stem cells are mesenchymal stem cells from human bone marrow. The cosmetic composition is used in the form of massage cream, nutrition cream, pack, and gel.본 발명은 피부 미용 및 성형용 조성물에 관한 것으로, 보다 상세하게는 백화사설초 추출물을 유효성분으로 함유하여 사람 중간엽줄기세포를 지방세포로 분화하는 것을 촉진시킴으로써 지방세포를 생성하여 피부의 볼륨과 탄력을 부여하는 미용 또는 성형 조성물에 관한 것이다.
