The present application relates to novel binder drug conjugates (ADCs), to active metabolites of these ADCs, to processes for preparing these ADCs, to the use of these ADCs for the treatment and/or prophylaxis of diseases and to the use of these ADCs for preparing medicaments for treatment and/or prophylaxis of diseases, in particular hyperproliferative and/or angiogenic disorders such as, for example, cancer diseases. Such treatments can be effected as monotherapy or else in combination with other medicaments or further therapeutic measures.本發明係關於新穎結合劑藥物結合物(ADC)、此等ADC之活性代謝物、用於製備此等ADC之方法、此等ADC用於治療及/或預防疾病之用途以及此等ADC用於製備供治療及/或預防疾病、尤其過度增生性病症及/或血管生成病症(諸如癌症疾病)之藥劑的用途。此類治療可作為單一療法或與其他藥劑或其他治療措施組合實施。
