An optical physiological signal measuring apparatus and a method for signal processing are provided. The method comprising measuring a target to be measured by using the optical physiological signal measuring apparatus; processing signals from each of sensors of the optical physiological signal measuring apparatus; a signal processing unit of the measuring apparatus determining whether a movement of the target is great than a threshold, and if the movement is sensed to be greater than the threshold, each of infrared ray (IR) signal and red signal are processed by spatial relationships corresponding to each of the sensors so as to reduce the motion artifact and obtain optical physiological signals of the target.一種光學生理訊號量測裝置以及訊號處理方法。訊號處理方法包括使用光學生理訊號量測裝置對待測物進行量測;將光學生理訊號量測裝置的各組感測單元所各自得到的訊號進行處理;訊號處理單元判斷待測物的晃動是否超過預定值;若晃動超過預定值時,各組感測單元所得到的各個紅外光訊號及各個紅光訊號依各組感測單元之對應空間幾何關係,將各個紅外光訊號及各個紅光訊號進行相對應調整,以降低動作干擾訊號,並獲得待測物的光學生理訊號。