The present invention relates to a novel family of covalent kinasesinhibitors.Compounds of this class have been found to have inhibitory activity againstmembers ofthe Tec kinase family, particularly ltk and/or RLK, TEC and/or combinationsthereof. Thepresent invention is directed to a compound of Formula I(see formula I)or pharmaceutically acceptable salt, solvate, solvates of salt, stereoisomer,tautomer,isotope, prodrug, complex or biologically active metabolite thereof, for usein therapy.
