M. Guy Roukens,Stefan Schulte-Merker,Dörte Schulte
申请号：
US15511703
公开号：
US20170342129A1
申请日:
2015.09.18
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention relates among others to a protein comprising a fragment of 30-240 amino acids of Collagen and calcium-binding EGF domain-containing protein 1 (CCBE1) having 0-10 amino acid substitutions with respect to the amino acid sequence of SEQ ID NO: 1, wherein said fragment comprises at least a collagen domain of CCBE1, or a variant thereof comprising 1, 2 or 3 amino acid substitutions. The invention further describes means and methods for the treatment of individuals with the protein or protein binding thereto.
