The Regents of the University of Colorado, a Body Corporate;Konkuk University;Advent Bio Holdings LLC.
发明人:
Charles A. Dinarello,James D. Crapo,Soohyun Kim
申请号:
US15921469
公开号:
US20180208681A1
申请日:
2018.03.14
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Embodiments herein report compositions of alpha-1 antitrypsin fusion polypeptides or peptide derivatives thereof. In certain embodiments, compositions and methods relate to generating a construct of use in pharmaceutically acceptable compositions to treat a subject in need of alpha-1 antitrypsin therapy or treatment. In other embodiments, compositions and methods disclosed herein concern linking alpha-1 antitrypsin or derivative thereof to an immune fragment.