I.E.R.F.C. EUROPEAN INSTITUTE FOR CYSTIC FIBROSIS RESEARCH
发明人:
Luigi Maiuri,Valeria Raia,Fabio Borella,Guido Kroemer
申请号:
US13895741
公开号:
US09132123B2
申请日:
2013.05.16
申请国别(地区):
US
年份:
2015
代理人:
摘要:
There is disclosed a combination of inhibitors of Tissue Transglutaminase (TG2), inhibitors of reactive oxygen species (ROS) and CFTR channel activators (potentiators) for separate, sequential or simultaneous administration to CF patients carrying the ΔF508-CFTR mutation, and pharmaceutical compositions thereof.