AICHER, THOMAS,BARR, KENNETH,SIMOV, VLADIMIR,THOMAS, WILLIAM,TOOGOOD, PETER,VAN HUIS, CHAD
申请号：
CA2871504
公开号：
CA2871504A1
申请日:
2013.05.03
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The invention provides bicyclic sulfone compounds, pharmaceutical compositions, methods of inhibiting RORy activity, reducing the amount of iL-17 in a subject, and treating immune disorders and inflammatory disorders using such bicyclic sulfone compounds. Another aspect of the invention provides a method of treating a subject suffering from a medical disorder. The method comprises administering to the subject a therapeutically effective amount of one or more bicyclic sulfone compounds described herein. In certain other embodiments, the disorder is rheumatoid arthritis.
