#$%^&*AU2014259527A120160526.pdf#####- 38 ABSTRACT ROBUST SEGMENTATION OF RETINAL PIGMENT EPITHELIUM LAYER 5 A method determining a retinal pigment epithelium identifies (510) a plurality of regions (805 1640, 1650 CCs) using captured image data of the eye and fits (730) a curve (1530,1660) into at least some of the regions. A curve score (L, Eqn. 7) is determined associated with the fitted curve using at least a distance Fig. 13) between the fitted curve and at least some of the regions in which a contribution (L eqn) of the regions to the curve score is 10 biased towards (asymmetric) regions below the fitted curve. These steps are repeated whereupon one of the fitted curves is selected (755), using the corresponding associated curve score, for classifying (760) some of the regions as forming at least a part of a retinal pigment epithelium (RPE). 4v55206 1 P1)FId6 npri Inrigp1/23 120 Y x 110 Fig. 1A 150 130 Tissue 140 reflectivity 10 Fig. 1B Fig. 1C
