Jonathan Betts-Lacroix,Laura Schaevitz,Daniel J. Ford
申请号：
US15363967
公开号：
US09700257B1
申请日:
2016.11.29
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Methods of measuring gut transit time in animals are presented. Steps include fasting an animal, then feeding it a food containing a fluorescent dye, and then monitoring bedding for fluorescent droppings by using an ultraviolet (UV) fluorescent excitation light that is in the visible range of the animal, and thus is perceived by the animal as daylight, while turning off human-visible white light so that a camera may record UV emissions without faint emission light being burned out by human-visible light. Such methods are fully automatic with continual monitoring in the home-cage of the animal. Animals may be multi-housed with automated animal-ID. A single camera may be used to observe fluorescent emission light, animal activity under white light, and animal activity under infrared (IR) light. The method may be repeated to create a measurement sequence to determine matching to a disease model.
