The present invention is related to sulfonamide derivatives of Formula (Ia)where the groups are as defined in the description, and use thereof in particularfor the treatment and/or prophylaxis of autoimmune disorders, inflammatorydiseases, cardiovascular diseases, neurodegenerative diseases, cancer,respiratory diseases and fibrosis, including multiple sclerosis, arthritis,emphysema, chronic obstructive pulmonary disease, liver and pulmonary fibrosis.