Guey-Jen Lee-Chen,Hsiu-Mei Hsieh,Guan-Chiun Lee,Ying-Chieh Sun
申请号：
US15238025
公开号：
US09629835B1
申请日:
2016.08.16
申请国别(地区):
US
年份:
2017
代理人:
摘要：
A method for treating tau-associated disease by administering a pharmaceutical composition comprising a quinoline derivative to a subject in need is disclosed. Particularly, a method for treating Alzheimer's disease by administering a pharmaceutical composition comprising a quinoline derivative to a subject in need is disclosed. The two disclosed quinoline derivatives have the inhibition effect for GSK-3β kinase activity, so as the two disclosed quinoline derivatives have the ability for inhibiting tau hyperphosphorylation or reducing tau aggregation.
