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製備載脂蛋白A-I (APO A-I)的方法
专利权人:
CSL LIMITED
发明人:
VUCICA, YVONNE,WARREN, GARY LEE
申请号:
HK16108249.4
公开号:
HK1220210A
申请日:
2016.07.13
申请国别(地区):
HK
年份:
2017
代理人:
摘要:
The present invention relates to processes of obtaining Apo A-1 from an Apo A-1 containing protein fraction (A), comprising suspending—the Apo A-1 containing protein fraction (A) in a buffer solution (B), removing impurities from the suspension while keeping the Apo A-1 proteins solubilized, followed by precipitating Apo A˜I from the suspension and collecting the Apo A-1 precipitate. Apo A-I obtained by such processes, reconstituted HDL obtained from such Apo A-1, and pharmaceutical compositions comprising such Apo A-I and/or reconstituted HDL also are provided.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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