Susana Conde-Ceide,Michiel Luc, Maria Van Gool,Maria Luz Martin-Martin
申请号：
US15500205
公开号：
US20170267682A1
申请日:
2015.07.30
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to novel 6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one derivatives as negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 2 (“mGluR2”). The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention or treatment of disorders in which the mGluR2 subtype of metabotropic receptors is involved.
