Jie Chen,Yan Chen,Nicholas A. Meanwell,Alicia Regueiro-Ren,Sing-Yuen Sit,Jacob Swidorski
申请号:
US15521957
公开号:
US09914747B2
申请日:
2015.11.12
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I and II:These compounds are useful for the treatment of HIV and AIDS.