CLARKE MICHAEL O&rsquo,NEIL HANRAHAN,MERTZMAN MICHAEL,CANALES EDA,LEW WILLARD,DOERFFLER EDWARD,LAZERWITH SCOTT E.,MORGANELLI PHILIP ANTHONY,WATKINS WILLIAM J.,CHONG LEE S.,CLARKE MICHAEL O&rsquoNEIL HANRAHAN
申请号：
NZ60081611
公开号：
NZ600816A
申请日:
2011.01.14
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
Disclosed are thiophene compounds of Formula (I): and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections. Example of compounds of formula (I) is: 5-(3,3-dimethyl-but-1-ynyl)-3-{ { 4-transmethyl-cyclohexanecarbonyI)-[4-(tetrahydro-pyran-4-yloxycarbonylamino)cyclohexyl]-amino} -thiophene-2-carboxylic acid.
